CRP thiab Hs-CRP: Dual Dimensions of Inflamation Monitoring

C-reactive protein (CRP), raws li ib tug tseem ceeb biomarker rau mob o thiab kis kab mob, nws rhiab heev variant Hs-CRP (high-rhiab heev C-reactive protein) tau ntxiv nthuav cov ciam teb ntawm kev kho mob daim ntawv thov. Cov pa CRP (nrog rau kev tshawb pom ntau ntawm 0.5 - 300 mg / L) tsom rau qhov nrawm. Kev kuaj mob Ntawm cov kab mob hnyav, cov teeb meem tom qab kev phais, thiab sepsis, thaum Hs-CRP (nrog rau kev kuaj pom ntau ntawm 0.1 - 10 mg / L) tuaj yeem ntes cov teeb liab qis qis, muab lub hauv paus tseem ceeb rau kev pheej hmoo ntawm cov kab mob plawv, kev tswj kev mob ntev, thiab tshuaj xyuas cov neeg noj qab haus huv. Kev sib koom ua ke ntawm kev tshawb nrhiav dual-nucleus ua tiav kev pab cuam los ntawm kev kho mob xwm txheej ceev mus rau kev tiv thaiv ntxov.

Cov ntaub ntawv pov thawj-raws li kev soj ntsuam daim ntawv thov scenarios

1. Precise Diagnosis thiab Stratification ntawm Kab mob Kab mob

Kev Tshawb Fawb Kev Sib Koom Tes ntawm CRP + PCT: Thaum CRP ≥ 50 mg / L nrog PCT ≥ 0.5 ng / mL, nws qhia tias muaj kab mob (qhov tshwj xeeb> 95%);

Distinguishing Viral Infections: Thaum CRP nce siab me ntsis (10 - 40 mg / L) thiab PCT yog qhov qub, kev kis kab mob lossis tsis kis kab mob yuav tsum tau suav tias yog qhov tseem ceeb.

2. Kev soj ntsuam kev pheej hmoo ntawm cov kab mob plawv

Kev soj ntsuam kev mob ntev: CRP ≥ 3 mg / L qhia tias muaj kab mob qis qis, uas cuam tshuam nrog kev pheej hmoo ntawm atherosclerosis;

Kev Ntsuas Kev Ntsuas Ntawm Kab Mob Coronary Heart Disease: Hauv cov neeg mob uas muaj mob plawv, yog tias CRP tseem nce siab (> 10 mg / L), nws qhia tias muaj kev mob tshwm sim tsis zoo thiab yuav tsum muaj kev kho mob hnyav.

3. Kev tswj cov kab mob autoimmune

Dynamic tracking ntawm inflammatory kev ua: CRP theem nyob rau hauv cov neeg mob Rheumatoid mob caj dab muaj kev cuam tshuam zoo nrog kev ua haujlwm ntawm tus kab mob (tus nqi phiaj: CRP

Kev ntsuam xyuas ntawm kev kho tau zoo: A ≥ 50% txo qis hauv CRP tom qab kev kho mob biologic qhia tau hais tias kev kho mob zoo.

4. Kev kho mob tom qab phais thiab mob hnyav

Kev ceeb toom ntawm kev mob ntshav qab zib: Kev ncua qeeb ntawm qib siab CRP lossis nce ntxiv (> 100 mg / L) tom qab kev phais qhia tias muaj kev pheej hmoo ntawm cov teeb meem nyuaj;

Kev txheeb xyuas ntxov ntawm sepsis: CRP> 100 mg / L ua ke nrog PCT ≥ 2 ng / mL tuaj yeem pib kho kev tiv thaiv kab mob sai sai.

5. Risk Stratification thiab tiv thaiv tshuaj rau cov kab mob plawv

Kev tshuaj xyuas cov neeg asymptomatic: Hs-CRP ≥ 2 mg / L qhia tias muaj kev pheej hmoo ntawm cov kab mob plawv. Ua ke nrog cov lipid profile (xws li LDL-C), nws tuaj yeem txhim kho tus qauv kev pheej hmoo (raws li pom zoo los ntawm ACC / AHA cov lus qhia);

Kev soj ntsuam ntawm kev cuam tshuam cov txiaj ntsig: Tom qab kev kho mob statin, Hs-CRP raug txo qis rau

Rau cov tib neeg kev kuaj mob ntawm tus kab mob inflammatory thiab CVD kev ntsuam xyuas txiav tawm tau raug pom zoo. Raws li hauv qab no:

6. Kev tswj cov kab mob ntev Metabolic

Kev Ceeb Toom Txog Kev Mob Ntshav Qab Zib: Kev nce siab ntxiv ntawm Hs-CRP (> 3 mg / L) hauv cov neeg mob ntshav qab zib hom 2 qhia tias muaj kev pheej hmoo ntawm cov teeb meem microvascular thiab cov hlab plawv raum, xav tau kev tswj hwm nruj;

Kev Saib Xyuas Kev Mob Ntshav Qab Zib: Qib Hs-CRP muaj kev cuam tshuam zoo nrog cov rog hauv cov hlab ntsha, muab ntau lub hauv paus rau kev cuam tshuam kev ua neej.

7. Precision Diagnosis thiab Kev Kho Mob autoimmune Disease

Kev txheeb xyuas qhov mob ntawm subclinical: Kev kuaj pom ntawm Hs-CRP tuaj yeem pab txheeb xyuas cov kab mob extrarenal (xws li kev cuam tshuam ntawm cov hlab plawv) hauv cov neeg mob rheumatoid mob caj dab thaum ntxov, coj kev kho ntau yam kev sib koom ua ke;

Kev kho kom zoo ntawm cov hom phiaj kho mob: Raws li kev kho mob ua ke nrog biologics, qib Hs-CRP tsawg dua 1 mg / L tuaj yeem siv los ua qhov pib siv rau kev kho mob kom tiav.

Lamuno (Fluorescence immunoassay platform): CRP/Hs-CRP dual hom, teeb tsa tus qauv kev lag luam tshiab

Kev kuaj pom dual-core nrog hloov pauv hloov tau yooj yim: Tib lub platform txhawb nqa ob qho tib si CRP (mob theem) thiab Hs-CRP (hloov theem) kev sim. Tsuas yog los ntawm kev hloov daim npav reagent, cov txiaj ntsig tuaj yeem ua tiav ib txhij hauv 15 feeb, ua tau raws li cov kev xav tau sib txawv.
Super precision kev ua tau zoo lav: Qhov rhiab heev ntawm Hs-CRP nce mus txog 0.5 mg / L, txheeb xyuas cov teeb liab qis qis;

Linear range: CRP 0.5-200 mg/L, seamlessly txuas thaum muaj xwm ceev thiab kev tswj kab mob ntev.

Compact tsim: haum rau ntau yam kev thov scenarios.

Los ntawm Kev Kho Mob Kub Ntxhov mus rau Kev Tiv Thaiv: Redefining Inflamation Management

Lamuno integrates dual nrhiav pom ntawm CRP thiab Hs-CRP, tawg los ntawm cov kev txwv ntawm ib txwm o kev tshuaj xyuas. Thaum muaj xwm txheej ceev, nws paub qhov chaw kis kab mob sai sai thiab qhia txog kev siv tshuaj tua kab mob; nyob rau hauv thaj tsam ntawm cov kab mob ntev, nws kwv yees cov xwm txheej ntawm cov hlab plawv 10 xyoo ua ntej, txhawb kev siv "tiv thaiv kab mob ua ntej nws tshwm sim". Qhov kev tsim kho tshiab no tsis yog txhim kho kev ua tau zoo ntawm kev faib cov peev txheej hauv kev kho mob tab sis tseem txhawb nqa cov neeg mob kev tswj hwm kev noj qab haus huv tas mus li los ntawm cov ntaub ntawv raug, muab kev txhawb nqa thev naus laus zis rau kev tiv thaiv kev noj qab haus huv rau pej xeem.