Hnub Ntiaj Teb Kev Mob caj dab yog lub ntiaj teb kev paub txog kev noj qab haus huv tau tsim txhua xyoo rau 12 Lub Kaum Hli los tsim kev paub txog cov kab mob rheumatic thiab musculoskeletal, nws cuam tshuam rau ib tus neeg lub neej thiab qhia tib neeg txog cov tsos mob & kev tiv thaiv thiab kev taw qhia rau kev kuaj mob thaum ntxov los daws cov teeb meem ntxiv. .
Qhov tseem ceeb ntawm World Arthritis Hnub (WAD)
Kev mob caj dab yog ib qho mob sib koom ua ke, uas cuam tshuam rau cov pob qij txha ntawm cov nqaij mos nyob ib ncig ntawm cov pob qij txha, thiab lwm cov ntaub so ntswg, ua rau mob pob qij txha thiab txhav.Ntau tshaj 100 hom mob caj dab muaj, tab sis feem ntau yog osteoarthritis thiab rheumatoid mob caj dab.Vim tsis muaj kev paub txog thiab kev txhawb nqa, kev mob caj dab thiab nws cov xwm txheej cuam tshuam tau ua rau lub neej nyob thoob plaws ntiaj teb.Tsis muaj kev kho mob tshwj xeeb rau kev mob caj dab, kev xaiv kev kho mob txawv raws li hom, yog li nws yog qhov tseem ceeb kom nkag siab txog cov cim & cov tsos mob thiab tau txais kev kuaj mob ntxov kom tau txais kev kho mob tsim nyog.
Feem ntau hom mob caj dab
Cov feem ntau muaj xws li osteoarthritis (OA), rheumatoid mob caj dab (RA), psoriatic mob caj dab (PsA), fibromyalgia thiab gout.Kev mob caj dab thiab lwm yam kab mob tuaj yeem ua rau mob hnyav, hloov lub neej ntawm ntau txoj kev.
Rheumatoid mob caj dab (RA) yog ib qho ntawm feem ntau cov kab mob sib koom ua ke, ntau dua rau cov poj niam hnub nyoog nruab nrab.Feem ntau manifested raws li ntev, symmetrical, zuj zus polyarthritis.Ntxiv nrog rau kev cuam tshuam cov pob qij txha, muaj ntau yam ntxiv-articular manifestations, xws li daim tawv nqaij, qhov muag, lub plawv, ntsws, ntshav system, thiab lwm yam.
Qhov feem ntau ntawm RA yog 0.5-1%, nrog rau poj niam rau txiv neej piv ntawm 3: 1.Nws yog 4 mus rau 5 npaug siab dua rau cov poj niam hnub nyoog qis dua 50 xyoo, tab sis tom qab 60 xyoo qhov piv tau kwv yees li 2 mus rau 1.Cov neeg mob rheumatoid mob caj dab feem ntau muaj qib siab C-reactive protein (CRP), uas yuav qhia tau tias muaj cov txheej txheem inflammatory hauv lub cev.Lwm yam kev kuaj ntshav zoo saib rau rheumatoid factor (RF) thiab anti-cyclic citrullinated peptide (anti-CCP) antibodies.
RA(Rheumatoid mob caj dab)
Rheumatoid mob caj dab yog ib qho mob ntev uas tuaj yeem cuam tshuam ntau dua li koj cov pob qij txha.Hauv qee tus neeg, tus mob tuaj yeem ua rau muaj ntau yam ntawm lub cev, nrog rau daim tawv nqaij, qhov muag, lub ntsws, lub plawv thiab cov hlab ntsha.
Cov kab mob autoimmune, rheumatoid mob caj dab tshwm sim thaum koj lub cev tiv thaiv kab mob ua yuam kev tawm tsam koj tus kheej cov ntaub so ntswg.
Tsis zoo li kev puas tsuaj ntawm osteoarthritis, rheumatoid mob caj dab cuam tshuam rau hauv ob sab phlu ntawm koj cov pob qij txha, ua rau mob o uas tuaj yeem ua rau pob txha yaig thiab pob txha deformity.
Anti-CCP Anti-Cyclic Citrullinated Peptide Antibody
Anti-cyclic citrullinated peptide antibody (Anti-CCP): Nws yog ib feem ntawm polypeptide ntawm cyclic polyguanidine protein thiab feem ntau yog IgG-type antibody.Anti-cyclic citrullinated peptide antibodies yog spontaneously secreted los ntawm B lymphocytes ntawm cov neeg mob rheumatoid mob caj dab (RA), thaum B lymphocytes ntawm cov neeg mob uas muaj lwm yam kab mob thiab ib txwm cov neeg tsis spontaneously secrete anti-cyclic citrullinated peptide antibodies.Yog li ntawd, nws muaj qhov rhiab heev thiab tshwj xeeb rau rheumatoid mob caj dab, thiab yog ib qho kev qhia tshwj xeeb rau kev kuaj mob thaum ntxov ntawm rheumatoid mob caj dab.
Anti-CCP (Anti-cyclic citrullinated peptides) yog ib hom autoantibody: ib qho tshuaj tiv thaiv uas ua haujlwm tawm tsam koj lub cev cov tshuaj tiv thaiv ib txwm muaj.Anti-CCP feem ntau tsim thaum koj muaj mob caj dab rheumatoid.Cov autoantibodies no pib tsom thiab tawm tsam lwm cov ntaub so ntswg noj qab haus huv.
Kev kuaj mob ntxov ntxov ntawm rheumatoid mob caj dab: anti-cyclic citrullinated antibodies tshwm sim 1-10 xyoo ua ntej kev kho mob tshwm sim ntawm rheumatoid mob caj dab, haum rau kev kuaj lub cev ntawm cov neeg noj qab haus huv thiab kev kuaj mob ntxov ntawm pab pawg muaj kev pheej hmoo siab.Tam sim no,Nws ntseeg tau tias qhov rhiab heev ntawm kev tiv thaiv cyclic citrullinated peptide antibodies rau kev kuaj mob rheumatoid mob caj dab yog 50% mus rau 78%, qhov tshwj xeeb yog 96%, thiab qhov zoo ntawm cov neeg mob thaum ntxov tuaj yeem ncav cuag 80%.
AehealthAnti-CCP Pkab
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Kev Ntsuas Kev Ntsuas nrawm tau txais cov txheej txheem Immunofluorescence Assay.
Cov khoom siv Anti-CCP kuaj pom kab ntau yog 10 ~ 500 U / mL;cov linear correlation coefficient ntawm theoretical concentration thiab ntsuas concentration tuaj yeem ncav cuag r≥0.990.Nws yog siv nrog Aehealth Lamuno X immunofluorescence tsom xam los saib xyuas kev kuaj mob ntxov thiab kev kho mob ntawm cov neeg mob rheumatism.
Cov tshuaj tiv thaiv CCP cuam tshuam nrog RA kev ua haujlwm tsis ua haujlwm.
Anti-CCP cov tshuaj tiv thaiv kwv yees RA puas.
Post lub sij hawm: Oct-12-2022